Andrew Scrivani (@AndrewScrivani on Twitter and Instagram) is a freelance photographer and a regular contributor to The New York Times. He writes the blog making SundaySauce.
There are certain dishes you need to be careful with when photographing so as to avoid the ?what the heck is that?? factor. You don?t want to rely on the headline or the text to explain to your audience exactly what it is seeing.
For this week?s Good Appetite column by Melissa Clark, we had that moment with the curry chicken recipe. Meats that are slow-cooked and have lots of sauce can sometimes be unidentifiable and lack form. The thighs and breasts look very similar when smothered in sauce, and they do not say ?chicken.?
It is no coincidence that a good number of food shots of chicken dishes include a drumstick. The leg does not have an identity crisis and has a shape that lends itself to multiple plating options.
You really want your image to capture the attention of people who merely scan the page looking for something interesting to eat or to make. You need to tap into the familiar and the recognizable in order to be evocative. Here, as in other arenas, a shapely leg can really catch the eye.
You know that something, somewhere, has gone seriously wrong when every last software update requires you to update a proprietary download manager before you can even think about getting your hands on whatever trivial bug fix that's on offer. [XKCD] More »
BERLIN (AP) ? Deutsche Telekom AG, the parent company of T-Mobile USA, is raising its bid for MetroPCS Communications Inc. in what it calls its "best and final offer."
The announcement late Wednesday comes ahead of a special shareholder meeting being held by Dallas-based MetroPCS Friday.
The deal would merge the fourth- and fifth-largest cellphone carriers in the U.S.
Telekom says the original offer had T-Mobile USA contributing $15 billion in shareholder loans to the combined company. The new offer reduces those loans to $11.2 billion, "significantly increasing the equity value of the combined company."
Telekom says it will also reduce the interest rate on those loans by 50 basis points.
The ownership structure remains unchanged, with 26 percent of shares being held by current MetroPCS shareholders and 74 percent by Deutsche Telekom.
Four ad execs who ran the first internet ad banner ? an AT&T ad that ran on HotWired in 1994 ? have all admitted to Digiday that, basically, they now hate it.
This isn't news, of course. Everyone in the ad business knows web ad banners are the lowest common denominator of web advertising.
Users largely ignore them. The creative space they offer is limited. It's just that replacing them with something more interesting or effective at scale is easier said than done.
Web ad banners persist because they can run virtually anywhere, across hundreds of millions of web sites and apps.
But it was nice to some straight talk from the people who created Frankenstein's monster.
G.M. O?Connell, founder of Modem Media, the agency that created the first banners, said:
The fact that it?s migrated from Prodigy to the Internet to the cell phone is a joke. The creativity is disappointing at best. It?s easy for me to say it sucks, but I don?t know what the better thing is.
Go to Digiday to see what Andrew Anker, CEO at HotWired; Joe McCambley, creative director at Modem Media; and Bill Clausen, the client at AT&T, the first banner ad advertiser, all had to say about it.
Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancerPublic release date: 9-Apr-2013 [ | E-mail | Share ]
Contact: Diana Quattrone diana.quattrone@fccc.edu 215-728-7784 Fox Chase Cancer Center
WASHINGTON, DC (April 9, 2013)Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively than cells from luminal types of the disease. The omega-3s worked against all types of cancerous cells, but the effect was observed to be stronger in triple-negative cell lines, reducing proliferation by as much as 90 percent. The findings will be presented at the AACR Annual Meeting 2013 on Tuesday, April 9.
Omega-3 fatty acids are found in oily fish like sardines and salmon, and also in oils derived from plants like hemp and flax. Previous studies suggest these compounds can negatively affect critical mechanisms in cancer cells, namely those responsible for proliferation and for apoptosis, or programmed cell death. Lead author on the study Thomas J. Pogash, a scientific technician in the Fox Chase Cancer Center lab of Jose Russo, MD, says the new work underscores the important role common compounds found in food may play in keeping cancer at bay.
"Diet can play a critical role in breast cancer prevention," says Pogash. "When you compare a western diet to a mediterranean diet, which has more omega-3s, you see less cancer in the mediterranean diet. They eat much more fish."
Breast cancer is a heterogeneous group of cancers comprising diseases that differ on the molecular level. Patients with different types of breast cancer respond differently to treatments. Four distinct categories of the disease are generally recognized. Two of those, luminal A and luminal B, grow in the luminal cells that line milk ducts in the breast and have receptors for estrogen and progesterone (prognosis is generally better for patients with luminal A than with luminal B). A third category includes tumors that test positive for the HER2 receptor.
Tumors in the fourth category, triple-negative, lack receptors for progesterone, estrogen, and a protein called HER2/neu. As a result, this type of disease is insensitive to treatments like trastuzumab, which disrupts the HER2 receptor, and tamoxifen, which targets the estrogen receptor.
Russo notes that no targeted therapies are currently available for patients diagnosed with triple-negative breast cancer. Combination chemotherapies are the standard of care for early-stage disease.
"This type of cancer, which is found more frequently in Latina and African-American women, is highly aggressive and has a low survival rate," says Russo. "There is not any specific treatment for it."
When a cancer cell digests omega-3s, the fatty acid is broken down into smaller molecules called metabolites. Russo, Pogash, and their colleagues tested the effect of large omega-3 parent molecules, as well as their smaller metabolic derivatives, on three luminal cell lines and seven lines that included basal-type triple-negative cells.
Omega-3 and its metabolites were observed to inhibit proliferation in all cell lines, but the effect was dramatically more pronounced in the triple-negative cell lines. In addition, the metabolites of omega-3 reduced the motility, or ability to move, by 20-60 percent in the triple-negative basal cell lines.
This study is part of a consortium between Fox Chase Cancer Center and Pennsylvania State University under a five-year grant awarded by the Komen Foundation. Russo is the principal investigator of the project at Fox Chase. Andrea Manni, MD, leader of the Pennsylvania State University team, has extended this work to animal models, studying the anticancer effects of omega-3s and its metabolites on mouse models of triple-negative breast cancer.
Russo and his colleagues are working on two related projects, one on the role of epigenetic events in the mechanism of cell transformation and another on the potential action of peptides of the hormone human chorionic gonadotropin (hCG) on breast cancer prevention.
###
In addition to Russo, Manni, and Pogash, investigators on this project included Ricardo Lpez de Cicco, Benjamin Pressly, and Irma H. Russo at Fox Chase Cancer Center; and Julie A. Himmelberger at DeSales University; and Shantu Amin, Krishne Gowda, and Karam El-Bayoumy at Pennsylvania State University.
Fox Chase Cancer Center, part of Temple University Health System, is one of the leading cancer research and treatment centers in the United States. Founded in 1904 in Philadelphia as one of the nation's first cancer hospitals, Fox Chase also was among the first institutions to receive the National Cancer Institute's prestigious comprehensive cancer center designation in 1974. Fox Chase researchers have won the highest awards in their fields, including two Nobel Prizes. Fox Chase physicians are routinely recognized in national rankings, and the Center's nursing program has achieved Magnet status for excellence three consecutive times. Fox Chase conducts a broad array of nationally competitive basic, translational, and clinical research and oversees programs in cancer prevention, detection, survivorship, and community outreach. For more information, call 1-888-FOX-CHASE (1-888-369-2427) or visit http://www.foxchase.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Omega-3 fatty acids more effective at inhibiting growth of triple-negative breast cancerPublic release date: 9-Apr-2013 [ | E-mail | Share ]
Contact: Diana Quattrone diana.quattrone@fccc.edu 215-728-7784 Fox Chase Cancer Center
WASHINGTON, DC (April 9, 2013)Researchers from Fox Chase Cancer Center have found that omega-3 fatty acids and their metabolite products slow or stop the proliferation, or growth in the number of cells, of triple-negative breast cancer cells more effectively than cells from luminal types of the disease. The omega-3s worked against all types of cancerous cells, but the effect was observed to be stronger in triple-negative cell lines, reducing proliferation by as much as 90 percent. The findings will be presented at the AACR Annual Meeting 2013 on Tuesday, April 9.
Omega-3 fatty acids are found in oily fish like sardines and salmon, and also in oils derived from plants like hemp and flax. Previous studies suggest these compounds can negatively affect critical mechanisms in cancer cells, namely those responsible for proliferation and for apoptosis, or programmed cell death. Lead author on the study Thomas J. Pogash, a scientific technician in the Fox Chase Cancer Center lab of Jose Russo, MD, says the new work underscores the important role common compounds found in food may play in keeping cancer at bay.
"Diet can play a critical role in breast cancer prevention," says Pogash. "When you compare a western diet to a mediterranean diet, which has more omega-3s, you see less cancer in the mediterranean diet. They eat much more fish."
Breast cancer is a heterogeneous group of cancers comprising diseases that differ on the molecular level. Patients with different types of breast cancer respond differently to treatments. Four distinct categories of the disease are generally recognized. Two of those, luminal A and luminal B, grow in the luminal cells that line milk ducts in the breast and have receptors for estrogen and progesterone (prognosis is generally better for patients with luminal A than with luminal B). A third category includes tumors that test positive for the HER2 receptor.
Tumors in the fourth category, triple-negative, lack receptors for progesterone, estrogen, and a protein called HER2/neu. As a result, this type of disease is insensitive to treatments like trastuzumab, which disrupts the HER2 receptor, and tamoxifen, which targets the estrogen receptor.
Russo notes that no targeted therapies are currently available for patients diagnosed with triple-negative breast cancer. Combination chemotherapies are the standard of care for early-stage disease.
"This type of cancer, which is found more frequently in Latina and African-American women, is highly aggressive and has a low survival rate," says Russo. "There is not any specific treatment for it."
When a cancer cell digests omega-3s, the fatty acid is broken down into smaller molecules called metabolites. Russo, Pogash, and their colleagues tested the effect of large omega-3 parent molecules, as well as their smaller metabolic derivatives, on three luminal cell lines and seven lines that included basal-type triple-negative cells.
Omega-3 and its metabolites were observed to inhibit proliferation in all cell lines, but the effect was dramatically more pronounced in the triple-negative cell lines. In addition, the metabolites of omega-3 reduced the motility, or ability to move, by 20-60 percent in the triple-negative basal cell lines.
This study is part of a consortium between Fox Chase Cancer Center and Pennsylvania State University under a five-year grant awarded by the Komen Foundation. Russo is the principal investigator of the project at Fox Chase. Andrea Manni, MD, leader of the Pennsylvania State University team, has extended this work to animal models, studying the anticancer effects of omega-3s and its metabolites on mouse models of triple-negative breast cancer.
Russo and his colleagues are working on two related projects, one on the role of epigenetic events in the mechanism of cell transformation and another on the potential action of peptides of the hormone human chorionic gonadotropin (hCG) on breast cancer prevention.
###
In addition to Russo, Manni, and Pogash, investigators on this project included Ricardo Lpez de Cicco, Benjamin Pressly, and Irma H. Russo at Fox Chase Cancer Center; and Julie A. Himmelberger at DeSales University; and Shantu Amin, Krishne Gowda, and Karam El-Bayoumy at Pennsylvania State University.
Fox Chase Cancer Center, part of Temple University Health System, is one of the leading cancer research and treatment centers in the United States. Founded in 1904 in Philadelphia as one of the nation's first cancer hospitals, Fox Chase also was among the first institutions to receive the National Cancer Institute's prestigious comprehensive cancer center designation in 1974. Fox Chase researchers have won the highest awards in their fields, including two Nobel Prizes. Fox Chase physicians are routinely recognized in national rankings, and the Center's nursing program has achieved Magnet status for excellence three consecutive times. Fox Chase conducts a broad array of nationally competitive basic, translational, and clinical research and oversees programs in cancer prevention, detection, survivorship, and community outreach. For more information, call 1-888-FOX-CHASE (1-888-369-2427) or visit http://www.foxchase.org.
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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Carnegie scientists have found that the plant species making up an ecosystem are better predictors of ecosystem chemistry than environmental conditions such as terrain, geology, or altitude. This is the first study using a new, high-resolution airborne, chemical-detecting instrument to map multiple ecosystem chemicals. The result, published in the April 8, 2013, Early Edition of the Proceedings of the National Academy of Sciences, is a key step toward understanding how species composition affects carbon, nitrogen and other nutrient cycling, and the effects of climate change, land use, and other ecosystem pressures.
Two important ecological goals are to understand the distribution and diversity of plants in their environment and how nutrients and energy flow through ecosystems. Both are essential to predict how the environment may change in the future, but untangling the relative importance of different influences has remained challenging.
Lead author Kyla Dahlin explained: "We used the high-resolution mapping capabilities of the Carnegie Airborne Observatory Airborne Taxonomic Mapping System (CAO AToMS), and found that the plant communities that make up Jasper Ridge Biological Preserve in Northern California were the strongest predictors. They explained 46% to 61% of the variation in plant chemical traits, and these traits hold the key to how ecosystems function."
The plant communities at Jasper Ridge include savanna/grasslands, evergreen oaks and chaparral, wetland ecosystems, and more. The researchers measured four traits mapped with CAO AToMS from the air: leaf nitrogen, leaf carbon, leaf water concentration, and canopy water content.
The researchers combined the airborne data with maps of known environmental regulators, such as terrain and geology, and maps of plant communities and land-use history to ask whether environmental conditions or plant communities were more indicative of the chemical variation of the vegetation. They found that environmental conditions played a role, but that plant communities were the stronger predictor.
Co-author Greg Asner, principal investigator of the CAO, commented, "The results are a powerful demonstration of the use of the latest airborne spectroscopic mapping techniques to understand the multiple chemicals in the foliage of vegetation, allowing us to relate the chemical information to biodiversity and environment. These are the tools of the future for ecological research and conservation science."
"This study is especially exciting for Carnegie because it answers questions about the roles of landscapes and plant communities that were posed by Carnegie investigators in the early decades of the 20th century," said co-author Chris Field, director of the Department of Global Ecology.
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Carnegie Institution: http://www.ciw.edu
Thanks to Carnegie Institution for this article.
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Tom Bihn has just announced a larger version of their previous Synapse 19 backpack. The Synapse 25 has five main design updates: Webbing Loops for Cache with Rails system Bottom Pocket Piping Bottom Webbing Loop More O-rings Reconfigured Organizer Pockets The addition of a secure laptop sleeve system transforms the Synapse 25 into a checkpoint [...]
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Public release date: 9-Apr-2013
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